Acetaldehyde-Related Pathology: Bridging the by Novartis Foundation

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Alcohol Clin Exp Res 25:976–981 Zimatkin S, Pronko SP, Vasiliou V, Gonzalez FJ, Deitrich RA 2006 Enzymatic mechanisms of ethanol oxidation in the brain. Alcohol Clin Exp Res 30:1500–1505 Zintzaras E, Stefanidis I, Santos M, Vidal F 2006 Do alcohol-metabolizing enzyme gene polymorphisms increase the risk of alcoholism and alcoholic liver disease? Hepatology 43:352–361 Removal of acetaldehyde from the body Richard A. Deitrich, Dennis Petersen* and Vasilis Vasiliou* Department of Pharmacology, University of Colorado School of Medicine, University of Colorado, HSC, PO Box 6511, Mail Stop 8303, Aurora, CO 80045 and *Department of Pharmaceutical Sciences, University of Colorado School of Pharmacy, 4200 E.

Pharmacogenetics 9:421–434 40 DEITRICH ET AL Vasiliou V, Pappa A, Estey T 2004 Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism. Drug Metab Rev 36:279–299 Vila R, Kurosaki M, Barzago MM et al 2004 Regulation and biochemistry of mouse molybdoflavoenzymes. The DBA/2 mouse is selectively deficient in the expression of aldehyde oxidase homologues 1 and 2 and represents a unique source for the purification and characterization of aldehyde oxidase. J Biol Chem 279:8668–8683 Von Wartburg JP, Berger D, Ris MM, Tabakoff B 1975 Enzymes of biogenic aldehyde metabolism.

The DBA/2 mouse is selectively deficient in the expression of aldehyde oxidase homologues 1 and 2 and represents a unique source for the purification and characterization of aldehyde oxidase. J Biol Chem 279:8668–8683 Von Wartburg JP, Berger D, Ris MM, Tabakoff B 1975 Enzymes of biogenic aldehyde metabolism. In: Gross MM (ed) Alcohol intoxication and withdrawal. Plenum Press, New York and London, p 119–138 Watanabe S, Sasahara K, Kinekawa F et al 2002 Aldehyde dehydrogenase-2 genotypes and HLA haplotypes in Japanese patients with esophageal cancer.

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Acetaldehyde-Related Pathology: Bridging the by Novartis Foundation
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