By Gaspar Delso, Sibylle Ziegler (auth.), Ignasi Carrio, Pablo Ros (eds.)
In compiling this textbook at the intriguing novel imaging modality of PET/MRI, the editors have introduced jointly a very foreign crew of specialists within the box. The ebook is split into elements. the 1st half covers method and kit and comprises chapters on simple molecular drugs, distinction brokers, MR attenuation and validation, and quantitative MRI and puppy movement correction. the second one a part of the booklet specializes in scientific functions in oncology, cardiology, and neurology. Imaging of significant neoplasms is roofed in a chain of person chapters. additional chapters deal with useful and metabolic cardiovascular examinations and significant vital fearful approach functions similar to mind tumors and dementias. This publication could be of curiosity to all radiologists and nuclear drugs physicians who desire to study extra in regards to the most recent advancements during this very important rising imaging modality and its applications.
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Additional info for PET/MRI: Methodology and Clinical Applications
15) that warrant retrospective corrections as proposed in , which, however, are not yet validated in clinical routine. 1 Description Standard MR-AC methods are based on the segmentation of three or four tissue classes (air, lung, and water or air, lung, fat, and water) from MR images that are acquired with dedicated sequences. However, segmentation may fail in routine application and cause inverted tissue classification. 16 shows a patient study where the tissue classes air and lung tissue (4-class segmentation) were inverted for a limited coaxial imaging range of the lower thorax, leading to incorrect attenuation correction of the PET activity in the thorax.
2013;32:237–46. Jezzard P. The physical basis of spatial distortions in magnetic resonance images, handbook of medical imaging. San Diego: Academic; 2000. p. 425–38. Blumhagen JO, Ladebeck R, Fenchel M, Scheffler K. MR-based field-of-view extension in MR/PET: B(0) homogenization using gradient enhancement (HUGE). Magn Reson Med. 2012. 24555. Epub ahead of print. Schwenzer NF, Schraml C, Müller M, Brendle C, Sauter A, Spengler W, Pfannenberg AC, Claussen CD, Schmidt H. Pulmonary lesion assessment: comparison of whole-body hybrid MR/PET and PET/CT imaging–pilot study.
Further show that completing the truncated attenuation map with data extracted from non-attenuation-corrected (NAC) PET data globally reduced these biases to below 10 % . The idea of using NAC-PET images to improve low-quality attenuation maps was already considered before the introduction of combined PET/CT systems and is based on the concurrent reconstruction of both, the PET emission activity distribution and the attenuation map . The improvements from using extended field-of-view attenuation maps [23, 24] in PET/MR are illustrated in Fig.
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